Ikeda A et al, Efficient elimination of RNA mycoviruses in Aspergillus species using RdRp-inhibitors ribavirin and 2'-C-methylribonucleoside derivatives. Front. Microbiol. (2022)
Ninomiya A et al, Antibacterial diphenyl ether production induced by co-culture of Aspergillus nidulans and Aspergillus fumigatus. Appl. Microbiol. Biotechnol. (2022)
Chiba Y et al, Splitting of RNA-dependent RNA Polymerase is Common in Narnaviridae: Identification of a type II Divided-RdRp from Deep-Sea Fungal Isolates. Virus Evol. (2021)
Takahashi H et al, Interspecies genomic variation and transcriptional activeness
of secondary metabolism-related genes in Aspergillus section Fumigati. Front. Fungal Biol. (2021)
Hagiwara D, Isolation of azole-resistant Aspergillus fumigatus from imported plant bulbs in Japan and the effect of fungicide treatment. J. Pest. Sci. (2020)
Zhao Y-J, Shirouzu T, Chiba Y, Hosaka K, Moriyama H, Urayama SI*, Hagiwara D. Identification of novel RNA mycoviruses from wild mushroom isolates in Japan. Virus Research, 325: 199045 (2023)
Chiba Y, Yabuki A, Takaki Y, Nunoura T, Urayama S*, Hagiwara D*. The first identification of a narnavirus in Bigyra, a marine-protist.
Microbes and Environments, 38: ME22077 (2023)
Ikeda A, Chiba Y, Kuroki M, Urayama S*, Hagiwara D*. Efficient elimination of RNA mycoviruses in Aspergillus species using RdRp-inhibitors ribavirin and 2'-C-methylribonucleoside
derivatives. Frontiers in Microbiology, 13:1024933 (2022)
Sakaguchi S, Urayama S, Takaki Y, Wu H, Suzuki Y, Nunoura T, Nakano T, Nakagawa S*. NeoRdRp: A comprehensive dataset for identifying RNA-dependent RNA polymerase of various RNA viruses from metatranscriptomic data. Microbes and Environments, 37: ME22001 (2022)
Kusuya Y, Bian C, Hagiwara D, Ban S, Takahashi H*. A novel Zn2-Cys6 transcription factor ClcA contributes to copper homeostasis in Aspergillus fumigatus. Current Genetics, 68: 605-617 (2022)
Bian C, Kusuya Y, Hagiwara D, Ban S, Lu Y, Nagayama M, Takahashi H*. Dysfunction of Ras-GAP protein AfgapA contributes to hypoxia fitness in Aspergillus fumigatus. Current Genetics, 68: 593-603 (2022)
Mizutani Y, Chiba Y, Urayama S, Tomaru Y, Hagiwara D, Kimura K*. Detection and Characterization of RNA Viruses in Red Macroalgae (Bangiaceae) and Their Food Product (Nori Sheets). Microbes and Environments 37.2 (2022): ME21084.
Oiki S, Nasuno R, Urayama S, Takagi H, Hagiwara D*. Intracellular production of reactive oxygen species and a DAF-FM-related
compound in Aspergillus fumigatus in response to antifungal agent exposure. Scientific Reports, 12: 13516 (2022)
Ninomiya A, Urayama S, Hagiwara D*. Antibacterial diphenyl ether production induced by co-culture of Aspergillus nidulans and Aspergillus fumigatus. Applied Microbiology and Biotechnology, 106: 4169–4185 (2022)
Kadoya S, Urayama S, Nunoura T, Hirai M, Takaki Y, Kitajima M, Nakagomi T, Nakagomi O, Okabe
S, Nishimura O, Sano D*. The Intrapopulation Genetic Diversity of RNA Virus
may Influence the Sensitivity of Chlorine Disinfection. Frontiers in Microbiology, 13: 839513 (2022)
Takahashi M, Wada K, Urayama S, Masuda Y, Nagasaki K*. Degenerate PCR Targeting the Major Capsid Protein
Gene of HcRNAV and Related Viruses. Microbes and Environments, 37.5: ME21075 (2022)
Hirai J*, Urayama S, Takaki Y, Hirai M, Nagasaki K, Nunoura T. RNA virosphere in a marine zooplankton community in the subtropical western North Pacific. Microbes and Environments, 37.5: ME21066 (2022)
Oiki S, Yaguchi T, Urayama S, Hagiwara D*. Wide distribution of resistance to the fungicides fludioxonil and iprodione in Penicillium species. PLoS One, 17.1: e0262521 (2022)
Nasuno R, Suzuki S, Oiki S, Hagiwara D, Takagi H*. Identification and functional analysis of GTP cyclohydrolase II in Candida glabrata in response to nitrosative stress. Frontiers in Microbiology, 13: 825121 (2022)
Chiba Y, Oiki S, Zhao Y-J, Nagano Y, Urayama S*, Hagiwara D*. Splitting of RNA-dependent RNA Polymerase is Common in Narnaviridae: Identification of a type II Divided-RdRp from Deep-Sea Fungal Isolates. Virus Evol. 7(2), veab095 (2021)
Takahashi H, Oiki S, Kusuya Y, Urayama S, Hagiwara D*. Intimate genetic relationships and fungicide resistance in multiple strains
of Aspergillus fumigatus isolated from a plant bulb. Environmental Microbiology, 23: 5621-5638 (2021)(プレスリリース)
Trabasso P, Matsuzawa T, Arai T, Hagiwara D, Mikami Y, Moretti ML, Watanabe A. Development and validation of LAMP
primer sets for rapid identification of Aspergillus fumigatus carrying the cyp51A TR46 azole resistance gene. Sci. Rep. 11: 17087 (2021)
Toyotome T*, Onishi K, Sato M, Kusuya Y, Hagiwara D, Watanabe A, Takahashi H. Identification of novel mutations contributing to azole tolerance of Aspergillus fumigatus through in vitro exposure to tebuconazole. Antimicrob Agents Chemother. 65: e0265720 (2021)
Yoshimi A, Hagiwara D, Ono M, Fukuma Y, Midorikawa Y, Furukawa K, Fujioka T, Mizutani O, Sato
N, Miyazawa K, Maruyama JI, Marui J, Yamagata Y, Nakajima T, Tanaka C,
Abe K*. Downregulation of the ypdA gene encoding an intermediate of His-Asp phosphorelay signaling in Aspergillus nidulans induces the same cellular effects as the phenylpyrrole fungicide fludioxonil.
Frontiers in Fungal Biology, 2: 675459 (2021)
Hirai M, Takaki Y*, Kondo F, Horie M, Urayama S, Nunoura T. RNA viral metagenome analysis from subnanogram dsRNA using
fragmented and primer ligated dsRNA sequencing (FLDS). Microbes and Environments, 36: ME20152 (2021).
Izumi T, Morioka Y, Urayama, S, Motooka D, Tamura T, Kawagishi T, ... & Fukuhara T. DsRNA Sequencing
for RNA Virus Surveillance Using Human Clinical Samples. Viruses, 13(7), 1310. (2021).
Takahashi H, Umemura M, Ninomiya A, Kusuya Y, Shimizu M, Urayama S, Watanabe A, Kamei K, Yaguchi T, Hagiwara D*. Interspecies Genomic Variation and Transcriptional Activeness of Secondary Metabolism-Related Genes in Aspergillus Section Fumigati. Frontiers in Fungal Biology, 2: 656751. doi: 10.3389/ffunb.2021.656751 (2021)
Uehara-Ichiki T*, Urayama S, Hirai M, Takaki Y, Nunoura T, Fujinaga M, Hanada K. Complete genome sequence
of Sikte (Sitke) waterborne virus, a member of the genus Tombusvirus. Archives of Virology, 166: 991-994 (2021)
Fujita R*, Inoue M, Takamatsu T, Arai H, Nishino M, Abe N, Itokawa K, Nakai
M, Urayama S, Chiba Y, Amoa-Bosompem M, Kunimi Y. Late Male-Killing Viruses in Homona magnanima Identified as Osugoroshi Viruses, Novel Members of Partitiviridae. Frontiers in microbiology, 11: 3558 (2021)
Chiba Y, Oiki S, Yaguchi T, Urayama S*, Hagiwara D*. Discovery of divided RdRp sequences and a hitherto unknown genomic complexity in fungal viruses. Virus Evol. 7(1), veaa101 (2020) (プレスリリース)
Tani S*, Nishio N, Kai K, Hagiwara D, Ogata Y, Tojo M, Sumitani JI, Judelson HS, Kawaguchi T. Chemical genetic
approach using beta-rubromycin reveals that a RIO kinase-like protein is
involved in morphological development in Phytophthora infestans. Sci. Rep. 10: 22326 (2020)
Takahashi-Nakaguchi A* , Shishido E, Yahara M, Urayama S, Ninomiya A, Chiba Y, Sakai K, Hagiwara D, Chibana H, Moriyama H, Gonoi T. Phenotypic and molecular biological analysis
of polymycovirus AfuPmV-1M from Aspergillus fumigatus: Reduced fungal virulence in a mouse infection model. Front. Microbiol. 11: 607795 (2020)
Abeysinghe G, Kuchira M, Kudo G, Masuo S, Ninomiya A, Takahashi K, Utada A, Hagiwara D, Nomura N, Takaya N, Obana N*, Takeshita N*. Fungal mycelia and bacterial
thiamine establish a mutualistic growth mechanism. Life Science Alliance, e202000878 (2020)(プレスリリース)(Science誌のEditors’ Choice)
Urayama S*, Doi N, Kondo F, Chiba Y, Takaki Y, Hirai M, Minegishi Y, Hagiwara D, Nunoura T. Diverged and active partitiviruses in lichen. Front. Microbiol. 11: 561344 (2020)
Morishita Y, Aoki Y, Ito M, Hagiwara D, Torimaru K, Morita D, Kuroda T, Fukano H, Hoshino Y, Suzuki M, Taniguchi T, Mori K, Asai T*. Genome mining-based discovery of fungal macrolides modified by GPI-ethanolamine phosphate transferase homologs. Org. Lett., 22: 5876-5879 (2020)
Ninomiya A, Urayama S, Suo R, Itoi S, Fuji S, Moriyama H, Hagiwara D*. Mycovirus-induced tenuazonic acid production in a rice blast fungus Magnaporthe
oryzae. Front. Microbiol. 11: 1641 (2020)
Chiba Y, Tomaru Y, Shimabukuro H, Kimura K, Hirai M, Takaki Y, Hagiwara D, Nunoura T, Urayama S *. Viral RNA genomes identified from marine macroalgae and a diatom. Microbes and Environments, 35(3): ME10016 (2020)
Kadoya S, Urayama S, Nunoura T, Hirai M, Takaki Y, Kitajima M, Nakagomi T, Nakagomi O, Okabe S, Nishimura O, Sano D. Bottleneck Size-Dependent Changes in the Genetic Diversity and Specific Growth Rate of a Rotavirus A Strain. Journal of Virology 94:e02083-19 (2020)
Urayama S*, Takaki Y, Hagiwara D, Nunoura T. dsRNA-seq reveals novel RNA virus and virus-like complete genome sequences from Hymeniacidon sp. sponge. Microbes and Environments. 35(2), ME19132 (2020)
Rocha M, Fabri J, Simões I, Silva-Rocha R, Hagiwara D, Cunha A, Goldman G, Cánovas D, and Malavazi I*. The cell wall integrity pathway contributes to the early stages of Aspergillus fumigatus asexual development. Appl. Environ. Microbiol., 86: e02347-19 (2020)
Takahashi-Nakaguchi A, Shishido E, Yahara M, Urayama S, Sakai K, Chibana H, Kamei K, Moriyama H, Gonoi T. Analysis of an intrinsic
mycovirus associated with reduced virulence of the human pathogenic fungus
Aspergillus fumigatus. Frontiers in Microbiology, 10:3045. doi: 10.3389/fmicb.2019.03045. (2020)
Sugahara A, Yoshimi A, Shoji F, Fujioka T, Kawai K, Umeyama H, Komatsu
K, Enomoto M, Kuwahara S, Hagiwara D, Katayama T, Horiuchi H, Miyazawa K, Nakayama M, Abe K*: A Novel Antifungal
Compound Z-705 Specifically Inhibits Protein Kinase C of Filamentous Fungi.
Appl. Environ. Microbiol., 85:e02923-18 (2019) doi: 10.1128/AEM.02923-18.
Paul S, Stamnes M, Thomas G, Liu H, Hagiwara D, Gomi K, Filler S, Moye-Rowley WS*: AtrR is an essential determinant of
azole resistance in Aspergillus fumigatus. mBio, 10: e02563-18 (2019)
José de Assis L, Manfiolli A, Mattos E, Malavazi I, Jacobsen ID, Brock
M, Cramer RA, Thammahong A, Hagiwara D, Ries LNA, Goldman GH*: Cooperation between protein kinase A (PKA) and
high osmolarity glycerol (HOG) response pathways cooperatively control
cell wall carbohydrate mobilization in Aspergillus fumigatus. mBio, 9: e01952-18 (2018)
Hagiwara D, Arai T, Takahashi H, Kusuya Y, Watanabe A*, Kamei K: Non-cyp51A azole-resistant Aspergillus fumigatus isolates with mutation in HMG-CoA reductase. Emerg. Infect. Dis., 24: 1889-1897 (2018)
Hagiwara D*, Takahashi H, Takagi H, Watanabe A, Kamei K: Heterogeneity in pathogenicity-related properties and stress tolerance in Aspergillus fumigatus clinical isolates. Med. Mycol. J., 59E: E63-E70 (2018)
Urayama S*, Takaki Y, Nishi S, Yoshida-Takashima Y, Deguchi S, Takai K, Nunoura T.
Unveiling the RNA virosphere associated with marine microorganisms. Molecular
Ecology Resources, 18:1444-1455, (2018) (Open Access)
Urayama S*, Takaki Y, Chiba Y, Zhao Y, Kuroki M, Hagiwara D, Nunoura T. Eukaryotic Microbial RNA Viruses—Acute or Persistent? Insights into Their Function in the Aquatic Ecosystem. Microbes and Environments, 37: ME22034 (2022) doi: 10.1264/jsme2.ME22034
Hagiwara D*: Current status of azole-resistant Aspergillus fumigatus isolates in East Asia: China, Japan, Korea, and Taiwan. Med. Mycol. J., 59E: E71-E76 (2018)
Toyotome T*, Hagiwara D, Takahashi H, Watanabe A, Kamei K: Emerging antifungal drug resistance
in Aspergillus fumigatus and among other species of Aspergillus. Curr. Fungal Infect. Rep., 12: 1-7 (2018)
Marina Takata, Moriyuki Kawauchi, Yasuo Onishi, Keishi Seno, Kiminori Shimizu, Syun-ichi
Urayama, Daisuke Hagiwara「Study on Aspergillus nidulans in soil culture
and teraction between fungi and soil microbiome」Best Poster Award, Tsukuba Global Science Week 2020、 Tsukuba
2019年度
Yuto Chiba, Syun-ich Urayama, Takashi Yaguchi, Daisuke Hagiwara「RNA virus diversity in Aspergillus fumigatus and its related species revealed by deep-sequencing method」Poster Award, The 8th Global Network Forum on Infection and Immunity, Chiba